"It was astonishing, almost too good to be true."
March 27, 2018 9:36 PM Subscribe
Dr. Neil Theise (@neiltheise), a liver pathologist, panpsychist, and Jewish Buddhist, published a paper today in which he and his collaborators announced the discovery of an entirely new human organ, the "Interstitium."
So, my husband's a liver pathologist at mt Sinai. I'll be asking him about this in the morning. Crazy.
posted by gaspode at 10:02 PM on March 27, 2018 [3 favorites]
posted by gaspode at 10:02 PM on March 27, 2018 [3 favorites]
It's also interesting how it's like if you're always looking something flattened out and prepared to highlight what you're looking for then you're not really examining reality fully.
posted by bleep at 10:11 PM on March 27, 2018 [4 favorites]
posted by bleep at 10:11 PM on March 27, 2018 [4 favorites]
This probably sounds crazy but I'm not a doctor so forgive my lunatic rantings.
This totally reminds me of a concept i learned about many eons ago from the martial practitioners of Tai Chi. As I recall, some practitioners were discussing how a particular martial style of Tai Chi, I believe it was Chen style, draws on the internal strength of the whole body, starting from something called the dan tein i believe, in the abdomen. These (non Chinese) folks were trying to explain it, those who claimed to be able to access it after many years of training, and they were saying that this internal, and unusual strength that certain practitioners could draw upon was perhaps related to the conscious activation and control of the normally untapped potential of the muscle fascia, rather than some superstitious source of magical strength as it was normally sold (to outsiders) at the time. Which, as it turns out, may not be so far fetched after all. Maybe the internal strength (chi) of the Chen family really is all connected all the way from fingers and toes to the center, the dan tien, as evidenced today by western science. So that's kind of cool.
posted by some loser at 10:33 PM on March 27, 2018 [4 favorites]
This totally reminds me of a concept i learned about many eons ago from the martial practitioners of Tai Chi. As I recall, some practitioners were discussing how a particular martial style of Tai Chi, I believe it was Chen style, draws on the internal strength of the whole body, starting from something called the dan tein i believe, in the abdomen. These (non Chinese) folks were trying to explain it, those who claimed to be able to access it after many years of training, and they were saying that this internal, and unusual strength that certain practitioners could draw upon was perhaps related to the conscious activation and control of the normally untapped potential of the muscle fascia, rather than some superstitious source of magical strength as it was normally sold (to outsiders) at the time. Which, as it turns out, may not be so far fetched after all. Maybe the internal strength (chi) of the Chen family really is all connected all the way from fingers and toes to the center, the dan tien, as evidenced today by western science. So that's kind of cool.
posted by some loser at 10:33 PM on March 27, 2018 [4 favorites]
This is old news to some alt-health massage therapists. When I learned therapeutic massage in 2015-16 they were calling this "fascia" as a shorthand. Any massage technique with the word "fascial" or "myofascial" in it has manipulating these structures as a goal. It was well understood that there are contiguous layers of connective tissue between every organ and muscle, and that some techniques of massage are directed specifically at them. I've personally experienced some powerful and strange physical and emotional effects from working upon these tissues in my own body, and caused and observed these effects in others. Frankly they can be easily underestimated and it's kind of hard to describe experientially because it was so intense.
Check out Anatomy Trains: Myofascial Meridians for Manual and Movement Therapists by Thomas Myers for a good example of one effort to describe and systematize these. A lot of my instructors had hypotheses for these structures being related to this or that chronic pain syndrome such as fibromyalgia.
Basically this Dr. Theise is not even the first anatomist to describe these or the first person to use dissection or cadaver study to trace them through the body.
posted by panhopticon at 11:16 PM on March 27, 2018 [15 favorites]
Check out Anatomy Trains: Myofascial Meridians for Manual and Movement Therapists by Thomas Myers for a good example of one effort to describe and systematize these. A lot of my instructors had hypotheses for these structures being related to this or that chronic pain syndrome such as fibromyalgia.
Basically this Dr. Theise is not even the first anatomist to describe these or the first person to use dissection or cadaver study to trace them through the body.
posted by panhopticon at 11:16 PM on March 27, 2018 [15 favorites]
Man, my interstitium has been itching for years.
posted by loquacious at 11:27 PM on March 27, 2018 [4 favorites]
posted by loquacious at 11:27 PM on March 27, 2018 [4 favorites]
This kind of reminds me of when I first heard that "the skin is the largest organ in the human body". It's quite unsatisfying as an organ, I feel like organs should be more modular and this is a joke answer to a trick question. It's like if someone said "the largest state in America is... the coastline!" The skin and the interstitium should be considered organ-supporting infrastructure or something like that, but not organs. But don't mind me, I'm not a doctor or a scientist or anything.
posted by L.P. Hatecraft at 12:28 AM on March 28, 2018 [11 favorites]
posted by L.P. Hatecraft at 12:28 AM on March 28, 2018 [11 favorites]
Take acupuncture, Theise said—that energetic healing jolt may be traced to the interstitium.
Wild speculation does not inspire confidence in the quality of the research.
posted by justsomebodythatyouusedtoknow at 12:38 AM on March 28, 2018 [15 favorites]
Wild speculation does not inspire confidence in the quality of the research.
posted by justsomebodythatyouusedtoknow at 12:38 AM on March 28, 2018 [15 favorites]
Conversely, wild speculation may be integral to the formation of quality research ideas.
posted by deadbilly at 12:41 AM on March 28, 2018 [25 favorites]
posted by deadbilly at 12:41 AM on March 28, 2018 [25 favorites]
Hooooo boy, there might be something interesting here but as someone who studied the science of pain and manual therapy for a few years this triggers one of my main alarms. People have been applying magic properties to fascia without evidence for a long time both as a business opportunity and as a "fun" mystical belief system. References to acupuncture, eastern medicine, and "potential radical changes to medicine" are all red flags.
Here's a long article on fascia from a massage / PT / manual therapy perspective. It's a bit orthogonal to the claims in this article, but I think it gets at how fascia attracts a lot of quackery.
And sure, it's hard to disambiguate the credibility of the doctors from this pop-sci article. And the understanding of the physical body isn't complete - we somehow only discovered the brain's lymphatic system a few years ago. But again, proceed with caution.
posted by MillMan at 12:53 AM on March 28, 2018 [19 favorites]
Here's a long article on fascia from a massage / PT / manual therapy perspective. It's a bit orthogonal to the claims in this article, but I think it gets at how fascia attracts a lot of quackery.
And sure, it's hard to disambiguate the credibility of the doctors from this pop-sci article. And the understanding of the physical body isn't complete - we somehow only discovered the brain's lymphatic system a few years ago. But again, proceed with caution.
posted by MillMan at 12:53 AM on March 28, 2018 [19 favorites]
it's the taint, isn't it.
right there, inbetweenium.
cain't git no more interstitial, imma think, ayup.
posted by mwhybark at 1:12 AM on March 28, 2018 [15 favorites]
right there, inbetweenium.
cain't git no more interstitial, imma think, ayup.
posted by mwhybark at 1:12 AM on March 28, 2018 [15 favorites]
I think the largest organ is going to turn out to be the friends we made along the way.
posted by Joe in Australia at 1:35 AM on March 28, 2018 [79 favorites]
posted by Joe in Australia at 1:35 AM on March 28, 2018 [79 favorites]
"I'm sure you're all aware that this week is National Gall Bladder Week, and so as sort of an educational feature at this point I thought I would acquaint you with some of the results of my recent researches into the career of the late Doctor Samuel Gall, inventor of the gall bladder, which certainly ranks as one of the more important technological advances since the invention of the joy buzzer and the dribble glass.
"Dr. Gall's faith in his invention was so dramatically vindicated last year, as you no doubt recall, when, for the first time in history in a nationwide poll, the gall bladder was voted among the top ten organs."
--- Professor Tom Lehrer.
posted by SPrintF at 2:52 AM on March 28, 2018 [6 favorites]
"Dr. Gall's faith in his invention was so dramatically vindicated last year, as you no doubt recall, when, for the first time in history in a nationwide poll, the gall bladder was voted among the top ten organs."
--- Professor Tom Lehrer.
posted by SPrintF at 2:52 AM on March 28, 2018 [6 favorites]
it's the taint, isn't it.
right there, inbetweenium.
cain't git no more interstitial, imma think, ayup.
Just a friendly reminder, there is still a little time left to submit your jokes for the MetaFilter April Fool's Day edition podcast.
posted by Fizz at 3:51 AM on March 28, 2018 [3 favorites]
right there, inbetweenium.
cain't git no more interstitial, imma think, ayup.
Just a friendly reminder, there is still a little time left to submit your jokes for the MetaFilter April Fool's Day edition podcast.
posted by Fizz at 3:51 AM on March 28, 2018 [3 favorites]
This is just a redefinition of fascia, right? They're not claiming to have discovered new structures, they're just saying that we should think of them as a monolithic organ rather than a collection of tissues. It's an alternative heuristic, a reclassification, not a discovery. They're saying that the fascia relates more to itself than to the structures it supports and connects.
Which is maybe true and maybe not, or maybe it's sometimes helpful to think of it that way and sometimes not, but it's a far cry from the "OMG new organ discovered, guess those arrogant doctors don't know everything after all, huh?" way that this is being sold. What they've done is taken a concept that's long been known to alternative medicine (including the empirically-supported parts of alternative medicine, like massage) given it a new name, and tried to pass it off as a major medical discovery.
Forgive me if I'm a bit underwhelmed.
posted by Anticipation Of A New Lover's Arrival, The at 4:35 AM on March 28, 2018 [9 favorites]
Which is maybe true and maybe not, or maybe it's sometimes helpful to think of it that way and sometimes not, but it's a far cry from the "OMG new organ discovered, guess those arrogant doctors don't know everything after all, huh?" way that this is being sold. What they've done is taken a concept that's long been known to alternative medicine (including the empirically-supported parts of alternative medicine, like massage) given it a new name, and tried to pass it off as a major medical discovery.
Forgive me if I'm a bit underwhelmed.
posted by Anticipation Of A New Lover's Arrival, The at 4:35 AM on March 28, 2018 [9 favorites]
Curious to a couple of the comments above ..."fascia"is not exactly an alternative medicine thing. Consider mainstream medical diagnoses (eg plantar fasciitis) that have it right there in the name.
posted by gaspode at 4:42 AM on March 28, 2018 [10 favorites]
posted by gaspode at 4:42 AM on March 28, 2018 [10 favorites]
The key thing about the discovery and its relation to fascia is that the interstitium is fluid-filled, which is not how these structures (apart from the lymphatic system) were primarily thought of before.
Looking forward to future work on this.
posted by lokta at 4:56 AM on March 28, 2018 [8 favorites]
Looking forward to future work on this.
posted by lokta at 4:56 AM on March 28, 2018 [8 favorites]
Speaking for myself, I was only trying to say that the concept of fascia-as-monolith is an alternative medicine thing, not the actual structures.
posted by Anticipation Of A New Lover's Arrival, The at 5:00 AM on March 28, 2018 [1 favorite]
posted by Anticipation Of A New Lover's Arrival, The at 5:00 AM on March 28, 2018 [1 favorite]
Dear Mr. Surgeon General, there are too many organs nowadays. Please eliminate three. I am not a crackpot.
posted by ejs at 5:11 AM on March 28, 2018 [14 favorites]
posted by ejs at 5:11 AM on March 28, 2018 [14 favorites]
This kind of reminds me of when I first heard that "the skin is the largest organ in the human body". It's quite unsatisfying as an organ, I feel like organs should be more modular and this is a joke answer to a trick question.
Barring the occasional pimple, eczema flareup, or insect bite, I find skin to be quite satisfying.
posted by GenderNullPointerException at 5:28 AM on March 28, 2018 [1 favorite]
Barring the occasional pimple, eczema flareup, or insect bite, I find skin to be quite satisfying.
posted by GenderNullPointerException at 5:28 AM on March 28, 2018 [1 favorite]
Your epidermis is showing!
posted by Schadenfreude at 6:20 AM on March 28, 2018 [5 favorites]
posted by Schadenfreude at 6:20 AM on March 28, 2018 [5 favorites]
Metafilter: It's the taint!
It does sound strange calling this an organ, but that feels nitpicky to argue. It's a bodily system that seems more widespread than thought, or maybe more organized ? Maybe it falls under the rubric of the lymphatic system, which is another system we don't have a great handle on.
posted by k5.user at 6:41 AM on March 28, 2018
It does sound strange calling this an organ, but that feels nitpicky to argue. It's a bodily system that seems more widespread than thought, or maybe more organized ? Maybe it falls under the rubric of the lymphatic system, which is another system we don't have a great handle on.
posted by k5.user at 6:41 AM on March 28, 2018
Theise said their team had submitted their paper to eight different journals (one sending the feedback that a new organ was “not of interest to a general audience”)
What the actual fuck. A. Since when is that the criteria for a medical journal?? and B. it's so inaccurate
Journals mostly only want to publish what they think will be interesting to readers. Sadly, they're really no different from any other magazine.
I previously wrote a long comment about the difficulties in publishing either negative or supposedly uninteresting findings.
I recalled then how, back in 2010, my colleagues and I wrote a completely novel secondary analysis regarding hypertension and cardiovascular outcomes with NSAIDs using data from the largest randomized NSAID cardiovascular outcomes trial ever conducted at the time (N=34,000). No one had ever published this type of analysis, and certainly not from a randomized study such as this one. We initially submitted it to Annals of Internal Medicine, one of the highest-rated journals in the world. We received a single -- 1!-- reviewer comment (which, in itself, is unheard of from this tier of medical journals): "I wanted to hate this study from the outset, but I could not find anything wrong with it." The reviewer noted the novelty and rigorusness of the study and suggested it be published. The editor, however, said it would not be of enough interest to the readership for publication.
posted by ssmug at 6:54 AM on March 28, 2018 [5 favorites]
What the actual fuck. A. Since when is that the criteria for a medical journal?? and B. it's so inaccurate
Journals mostly only want to publish what they think will be interesting to readers. Sadly, they're really no different from any other magazine.
I previously wrote a long comment about the difficulties in publishing either negative or supposedly uninteresting findings.
I recalled then how, back in 2010, my colleagues and I wrote a completely novel secondary analysis regarding hypertension and cardiovascular outcomes with NSAIDs using data from the largest randomized NSAID cardiovascular outcomes trial ever conducted at the time (N=34,000). No one had ever published this type of analysis, and certainly not from a randomized study such as this one. We initially submitted it to Annals of Internal Medicine, one of the highest-rated journals in the world. We received a single -- 1!-- reviewer comment (which, in itself, is unheard of from this tier of medical journals): "I wanted to hate this study from the outset, but I could not find anything wrong with it." The reviewer noted the novelty and rigorusness of the study and suggested it be published. The editor, however, said it would not be of enough interest to the readership for publication.
posted by ssmug at 6:54 AM on March 28, 2018 [5 favorites]
A somewhat drier - but still interesting - take from Scientific American.
posted by Mr.Know-it-some at 6:55 AM on March 28, 2018 [2 favorites]
posted by Mr.Know-it-some at 6:55 AM on March 28, 2018 [2 favorites]
Here's a Nat Geo take that at least brings in one outside opinion (of the standard "intriguing but more study needed" variety, but still better than nothing.)
Rejected by eight medical journals and published in something more general interest may be a sign that it is so paradigm-shattering the establishment can't handle it, but it may also mean the impact is not as huge as the authors put forth to Daily Beast writers. (I do admit I may be biased by the alt-medicine stylings of the hype.)
posted by mark k at 6:59 AM on March 28, 2018 [1 favorite]
Rejected by eight medical journals and published in something more general interest may be a sign that it is so paradigm-shattering the establishment can't handle it, but it may also mean the impact is not as huge as the authors put forth to Daily Beast writers. (I do admit I may be biased by the alt-medicine stylings of the hype.)
posted by mark k at 6:59 AM on March 28, 2018 [1 favorite]
Interstitium? Damn near killed 'em!
No, seriously, it's an analog to the lymphatic system, and is a vector for cancer to metastatize and--wait, where are you going
posted by Mayor West at 7:05 AM on March 28, 2018 [6 favorites]
No, seriously, it's an analog to the lymphatic system, and is a vector for cancer to metastatize and--wait, where are you going
posted by Mayor West at 7:05 AM on March 28, 2018 [6 favorites]
The "Jewish Buddhist" link is broken.
posted by Sangermaine at 7:55 AM on March 28, 2018
posted by Sangermaine at 7:55 AM on March 28, 2018
Rejected by eight medical journals and published in something more general interest may be a sign that it is so paradigm-shattering the establishment can't handle it, but it may also mean the impact is not as huge as the authors put forth to Daily Beast writers.
"They laughed at Newton. They laughed at Galileo. But they also laughed at Bozo The Clown."
posted by murphy slaw at 8:03 AM on March 28, 2018 [6 favorites]
"They laughed at Newton. They laughed at Galileo. But they also laughed at Bozo The Clown."
posted by murphy slaw at 8:03 AM on March 28, 2018 [6 favorites]
The c missing link is Dr. Theise' s appearance on the Meditate THIS! podcast - "Get one step closer to the meaning of life with Dr. Neil Theise, a diagnostic liver pathologist and world-renowned pioneer in stem cell research. Neil's career in science and medicine combined with his long-term practice of Zen Buddhism has opened new doors into thinking about consciousness, complexity theory, panpsychism, complimentarity, and other things Pete and Jay had never heard of before. "
posted by the man of twists and turns at 8:12 AM on March 28, 2018
posted by the man of twists and turns at 8:12 AM on March 28, 2018
This is published in Scientific Reports, which is a just-OK journal even though it's published by Nature. It's kind of meant as a repository for things that are scientifically/technically flawless but not expected to have a super high impact (i.e. number of subsequent citations).
Insofar as the manuscript is concerned, there's absolutely no evidence that these findings will have an impact on diagnosis or therapy. They describe (and characterize quite well) an interesting and previously poorly described structure, which is great. However, without a definitive link to something bigger, it's no surprise they got shot down from other journals.
posted by Maecenas at 9:41 AM on March 28, 2018 [3 favorites]
Insofar as the manuscript is concerned, there's absolutely no evidence that these findings will have an impact on diagnosis or therapy. They describe (and characterize quite well) an interesting and previously poorly described structure, which is great. However, without a definitive link to something bigger, it's no surprise they got shot down from other journals.
posted by Maecenas at 9:41 AM on March 28, 2018 [3 favorites]
I find it interesting that the original paper does not attempt to define the interstitium as an "organ", yet every science news outlet I've seen has run with that angle: Daily Beast in the OP, Scientific American linked above, but also Ars Technica, National Geographic, AAAS' EurekAlert, NBC News and many more.
The authors report that by utilizing a new tissue preparation technique, they have been able to retain the structure of the interstitial space from various parts of the body—structure that traditional prep techniques normally compress by dehydration or otherwise alter the shape of. OK, that's interesting and probably worthy of publication. They say that the interstitial spaces from these different parts of the body look very similar to each other. Cool.
But I feel like that's the limit of their findings. Their special tissue preparation technique maintains structure by preserving the fluid in between cells, and the authors get in a real tizzy about there being SO MUCH FLUID and how it could be flowing all over the place and moving cancer cells and proinflammatory molecules. But that's a lot of speculation and I don't know if there's really anything new about that knowledge. The interstitial space is known to have lots of fluid in it, and I think any histologist worth their degree will outright tell you that preparation techniques dehydrate tissues and alter shapes. It doesn't mean that everyone's understanding of the interstitial space is mistaken.
I think of this paper and the buzz it's getting much like the report from about a year ago on the mesentery. Credit to those authors for at least outright owning their argument that the mesentery should be classified as an organ—mostly because they want to raise awareness of it and drive research, which, OK fine that's a noble goal.
On preview, what Maecenas said.
posted by cyclopticgaze at 10:15 AM on March 28, 2018 [8 favorites]
The authors report that by utilizing a new tissue preparation technique, they have been able to retain the structure of the interstitial space from various parts of the body—structure that traditional prep techniques normally compress by dehydration or otherwise alter the shape of. OK, that's interesting and probably worthy of publication. They say that the interstitial spaces from these different parts of the body look very similar to each other. Cool.
But I feel like that's the limit of their findings. Their special tissue preparation technique maintains structure by preserving the fluid in between cells, and the authors get in a real tizzy about there being SO MUCH FLUID and how it could be flowing all over the place and moving cancer cells and proinflammatory molecules. But that's a lot of speculation and I don't know if there's really anything new about that knowledge. The interstitial space is known to have lots of fluid in it, and I think any histologist worth their degree will outright tell you that preparation techniques dehydrate tissues and alter shapes. It doesn't mean that everyone's understanding of the interstitial space is mistaken.
I think of this paper and the buzz it's getting much like the report from about a year ago on the mesentery. Credit to those authors for at least outright owning their argument that the mesentery should be classified as an organ—mostly because they want to raise awareness of it and drive research, which, OK fine that's a noble goal.
On preview, what Maecenas said.
posted by cyclopticgaze at 10:15 AM on March 28, 2018 [8 favorites]
The key thing about the discovery and its relation to fascia is that the interstitium is fluid-filled, which is not how these structures (apart from the lymphatic system) were primarily thought of before.
That's not a "new discovery" either, they just proved what has been a fairly wide understanding about the tissue. Proper hydration has been known, at least to manual therapists, to have an effect on fascia for a while now.
posted by P.o.B. at 10:16 AM on March 28, 2018 [2 favorites]
That's not a "new discovery" either, they just proved what has been a fairly wide understanding about the tissue. Proper hydration has been known, at least to manual therapists, to have an effect on fascia for a while now.
posted by P.o.B. at 10:16 AM on March 28, 2018 [2 favorites]
Obviously, the media reports leave something out. The author is a liver pathologist (reportedly) and is quoted as discovering this “interstitium” using confocal microscopy, which allows inspection of tissue without (as much) fixation.
Yet, the interstitial space generally and the hepatic interstitial space in particular has been known and studied for years. Indeed, the perisinusoidal space (outside the sinusoids, which are continuations of the capillaries, but lined by a specialized fenestrated endothelium) was described by Joseph Disse in the 1890s - and goes by the eponym “the space of Disse.” This interstitial space is continuous with hepatic venous capillaries as well as the lymphatic system, which has been demonstrated by various perfusion studies over the years.
The more generic interstitial space is separated from the vascular space by endothelium which is a layer of cells connected by tight junctions and is not permeable to macromolecules. (Certain portal circulations, like the liver, pituitary, etc. are special cases with specialized endothelium.) It is also well-established that certain disease states and toxins chiefly affect endothelial function, like sepsis (generally), ARDS/non-cardiogenic pulmonary edema (the lung endothelium), and so on.
So I’m not surprised of the rejection of the paper. Still this is an area of active research, including characterization of the diTerence’s between various endothelial cell types such as those found in the “interstitium” and vascular endothelium.
posted by sudogeek at 10:35 AM on March 28, 2018 [5 favorites]
Yet, the interstitial space generally and the hepatic interstitial space in particular has been known and studied for years. Indeed, the perisinusoidal space (outside the sinusoids, which are continuations of the capillaries, but lined by a specialized fenestrated endothelium) was described by Joseph Disse in the 1890s - and goes by the eponym “the space of Disse.” This interstitial space is continuous with hepatic venous capillaries as well as the lymphatic system, which has been demonstrated by various perfusion studies over the years.
The more generic interstitial space is separated from the vascular space by endothelium which is a layer of cells connected by tight junctions and is not permeable to macromolecules. (Certain portal circulations, like the liver, pituitary, etc. are special cases with specialized endothelium.) It is also well-established that certain disease states and toxins chiefly affect endothelial function, like sepsis (generally), ARDS/non-cardiogenic pulmonary edema (the lung endothelium), and so on.
So I’m not surprised of the rejection of the paper. Still this is an area of active research, including characterization of the diTerence’s between various endothelial cell types such as those found in the “interstitium” and vascular endothelium.
posted by sudogeek at 10:35 AM on March 28, 2018 [5 favorites]
Color me unimpressed. The interstitium has been recognized for decades (centuries?) as the scaffolding on which everything else in the body is built. In medical school, we used to joke about it being the reason why there was always room for dessert (as in, "Man, I'm so full from eating 3 slices of free pizza at study group, but sure, I'll have a cupcake, that just fits into the interstitium!")
At best, this is a status upgrade for the Hufflepuff of the body. It's like Pluto's downgrade but in reverse. #NinePlanets4Lyfe
posted by basalganglia at 12:54 PM on March 28, 2018 [5 favorites]
At best, this is a status upgrade for the Hufflepuff of the body. It's like Pluto's downgrade but in reverse. #NinePlanets4Lyfe
posted by basalganglia at 12:54 PM on March 28, 2018 [5 favorites]
You lost me at acupuncture.
posted by complaina at 7:15 PM on March 28, 2018 [3 favorites]
posted by complaina at 7:15 PM on March 28, 2018 [3 favorites]
How do Jewish Buddhists pray?
Shal-ommmmmmmmmmmmmm.
posted by miyabo at 7:43 PM on March 28, 2018 [3 favorites]
Shal-ommmmmmmmmmmmmm.
posted by miyabo at 7:43 PM on March 28, 2018 [3 favorites]
Tom Meyers, author of Anatomy Trains, made a statement on his blog about this 'new' discovery.
posted by P.o.B. at 12:18 PM on March 30, 2018 [1 favorite]
posted by P.o.B. at 12:18 PM on March 30, 2018 [1 favorite]
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What the actual fuck. A. Since when is that the criteria for a medical journal?? and B. it's so inaccurate
posted by bleep at 9:48 PM on March 27, 2018 [7 favorites]